I've been taking Zonisamide from June 22, which is just under one week. Friday I double the dose.
So far I've gone to bed feeling sick two or maybe three of those days in a state of real discomfort. Basically stomach upset. Now tonight I feel OK, I think so long as I don't have a very heavy meal at night and am careful to take the drug after the meal then I'm OK.
I've felt a little discomfort off and on tonight but nowhere near the amount I had last night or the night before.
At this point I have to persevere with the therapy, and it may work eventually, but I think the real success will come when my nerves get blocked at the Pain and Anesthesia Clinic at UNC; and perhaps if the sleep study I am scheduled for in August yields results.
I have some Zofran left over from my R-CHOP days; maybe I should have some of that next time I take my Zonisamide.
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